Welcome to the Center for Functional Evaluation of Rare Variants
Our Mission
The Center for Functional Evalulation of Rare Variants (CFERV) is advancing our understanding of rare genetic variants by exploring the functional effects of these changes on the expressed protein. CFERV is established by a High Impact Neuroscience Resource from NIH/NINDS and the generous support of private donors.
Gene Testing and Analysis
CFERV accepts requests from clinicians and research scientists interested in the functional consequences of gene variation. We currently analyze function for all glutamate receptor gene families.
CFERV tests GRIN, GRIA, GRIK, and GRID gene variants upon request. CFERV is a national clearing house for information on rare variants in the GRIN, GRIA, GRIK, and GRID genes. We provide results of functional analyses to clinicians and research scientists.
Make A Gift
100% of all donations go to the support of CFERV activities including the evaluation of functional effects of new patient-derived genetic variants and the maintenance of a publicly accessible database for clinicians, scientists, and parents to obtain information about functional effects of genetic variants. Your participation is a critical component of our ability to serve patients and advance our understanding of genetic
